Poly(dihydroferulic acid) a biorenewable polyethylene terephthalate mimic derived from lignin and acetic acid and copolymers thereof

ABSTRACT

A biorenewable thermoplastic, poly(dihydroferulic acid) (PHFA), which is an effective polyethylene terephthalate (PET) mimic is disclosed. The PHFA can be prepared by the self-condensation of acetyldihydroferulic acid as the monomer that can be synthesized from the starting material-ferulic acid, which can be isolated from lignin, rice bran, or other biorenewable sources.

CROSS-REFERENCE TO RELATED APPLICATIONS

This application is a divisional of U.S. application Ser. No.13/674,561, filed Nov. 12, 2012, which is a continuation-in-part ofInternational Patent Application No. PCT/US2011/036181, filed May 12,2011, which claims the benefit of U.S. Provisional Application Ser. No.61/334,342, filed May 13, 2010, the disclosures of which are herebyincorporated by reference herein in their entireties, including anyfigures, tables, or drawings.

The subject invention was made with government support under theNational Science Foundation, Contract No. 0848236. The government hascertain rights to this invention.

BACKGROUND OF INVENTION

The development of new polymeric materials from renewable resources isgaining considerable attention. Biorenewability is directed toward asustainable raw material supply where the raw material is renewed fromplants or other biological matter, generally through agricultural.Biorenewable polymers are pursued as environmentally friendlyreplacements for commodity plastics from petrochemical startingmaterials. The goal is to use low cost readily available startingmaterials from biorenewable resources such that biorenewable polymerscan be competitive with current commercial plastics in the marketplace.

Rather than creating a biorenewable polymer directly from a crop withthe limitations imposed by nature with respect to processing andproperties, a practical goal is to develop polymers from monomersderived from biorenewable sources that are chemically identical to or amimic of those derived from petroleum sources. In this manner the marketfor the biorenewable polymer need not be generated, as materials withthe properties to be provided by the new polymers are presentlycommodities. Additionally, polymerization techniques and processingtechnologies that are developed along with the monomers for thebiorenewable polymers can be designed in light of the methods currentlyused to produce the commodity polymers.

In general, thermoplastics constitute more than 65% of all globalpolymer demand and have the possibility to be recycled bymelt-processing. Thermoplastic biorenewable polymers are potentiallyrecyclable, which is advantageous for consumer packaging and other highvolume needs. A commercially important thermoplastic or its mimic thatis prepared by a step-growth process is a particularly practical targetfor biorenewable monomers.

Step-growth produced polyethylene terephthalate (PET) is the third mostcommon synthetic polymer and accounts for about 20% of world polymerproduction. This aromatic/aliphatic polyester has very useful thermalproperties that are not displayed in an all-aliphatic commoditythermoplastic. PET displays a glass transition temperature (T_(g)) of67° C. and a melting temperature (T_(m)) of 265° C. The key aromaticmonomer for preparation of PET, terephthalic acid, is derived frompetroleum, and its complementary monomer, ethylene glycol, is derivedfrom petroleum or natural gas.

The design of a sustainable PET mimic requires an aromatic monomer. Tothis end, an attractive biorenewable source for the aromatic monomer islignin. Lignin is found in all vascular plants and is the second mostabundant naturally-occurring organic polymer, making up approximately30% of wood. The extraction of lignin from wood is carried out in largescale in the paper pulping industry, and as such, constitutes anattractive source for a PET mimic. In addition to lignin, the bran ofrice and maize offers attractive opportunities to harvest potentiallyuseful aromatic/aliphatic monomers. One such monomer, ferulic acid(4-hydroxy-3-methoxycinnamic acid), is found in the cell walls ofseveral plants and is one of the most abundant hydroxycinnamic acids inthe plant world. Ferulic acid enhances the rigidity and strength ofplants from several families including various grasses such asGraminaceae, vegetable plants from the Solanace family, as well as manyflowering plants from the groups of both Monocots as well as Dicots.Seeds of coffee, apple, artichoke, peanut, and orange, as well as bothseeds and cell walls of rice, wheat, and oats all contain this phenolicphytochemical. Perhaps the greatest naturally occurring source comesfrom maize bran, a plant with highly cross-linked cell walls containingesterified ferulic acid, making the structure rather impervious toenzymatic degradation. To this end the preparation of material withcomparable thermal properties to polyethylene terephthalate (PET) andpolystyrene (PS), two of the most widely used synthetic petroleumderived polymers, based on a functionalized ferulic acid, is a desirableway to achieve the goal of a biorenewable polymer.

BRIEF SUMMARY

An embodiment of the invention is directed to a biorenewablethermoplastic homopolymer comprising poly(dihydroferulic acid), which isa PET mimic. The poly(dihydroferulic acid) can have at least one acetoxyend group. In other embodiments of the invention an aromatic/aliphaticpolymer of the structure:

wherein R¹, R², R³, R⁴ are independently H or OR where R is C₁ to C₆alkyl can be produced and can have an acetoxy end-group. Some of thesepolymers can be prepared from monomers that can be derived frombiorenewable resources.

An embodiment of the invention is directed to a method of preparingpoly(dihydroferulic acid) where acetyldihydroferulic acid and a catalystare combined and the acetyldihydroferulic acid polymerized topoly(dihydroferulic acid) with the liberation of acetic acid. Theacetyldihydroferulic acid can be derived from a biorenewable source, forexample lignin. In another embodiment of the invention, thepolymerization of a monomer of the structure:

where R¹, R², R³, R⁴ are independently H or OR where R is C₁ to C₆ alkylcan be combined with a catalyst and polymerized to any polymer of thestructure:

wherein R¹, R², R³, R⁴ are independently H or OR where R is C₁ to C₆alkyl with the liberation of acetic acid. For these polymerizations, thecatalyst comprises an oxide, alkoxide or acetate of Sb, Ti, Ge, Hg, Si,Zr, Al, or Zn, such as Zn(OAc)₂. The polymerization can be carried outunder vacuum and can be carried out at a temperature of 200 to 300° C.

An embodiment of the invention is directed to a copolymer ofacetylferulic acid and acetyldihydroferulic acid for the preparation ofa thermoplastic. Another embodiment of the invention is directed to amethod for the copolymerizing acetylferulic acid andacetyldihydroferulic acid with a variety of comonomer ratios.

BRIEF DESCRIPTION OF DRAWINGS

FIG. 1 shows a synthetic scheme for the preparation ofpoly(dihydroferulic acid), PHFA, from biorenewable feedstocks inaccordance with an embodiment of the invention.

FIG. 2 is a ¹H NMR spectrum of acetylferulic acid.

FIG. 3 is a ¹³C NMR spectrum of acetylferulic acid.

FIG. 4 is a ¹H NMR spectrum of acetyldihydroferulic acid.

FIG. 5 is a ¹³C NMR spectrum of acetyldihydroferulic acid.

FIG. 6 is a ¹H NMR spectrum of PHFA according to an embodiment of theinvention with peak assignment indicated that was used for end-groupanalysis for the determination of the degree of polymerization.

FIG. 7 is a ¹³C NMR spectrum of PHFA according to an embodiment of theinvention.

FIG. 8 is a DSC thermogram of PHFA in accordance with an embodiment ofthe invention.

FIG. 9 is a TGA plot for PHFA in accordance with an embodiment of theinvention.

FIG. 10 shows a synthetic scheme for the preparation ofpoly(dihydroferulic acid-co-ferulic acid) in accordance with anembodiment of the invention.

FIG. 11 is a DSC thermogram of 10:90 poly(ferulic acid-co-dihydroferulicacid), in accordance with an embodiment of the invention.

FIG. 12 is a TGA plot for 10:90 poly(ferulic acid-co-dihydroferulicacid), in accordance with an embodiment of the invention.

FIG. 13 is a DSC thermogram of 30:70 poly(ferulic acid-co-dihydroferulicacid), in accordance with an embodiment of the invention.

FIG. 14 is a TGA plot for 30:70 poly(ferulic acid-co-dihydroferulicacid), in accordance with an embodiment of the invention.

FIG. 15 is a DSC thermogram of 70:30 poly(ferulic acid-co-dihydroferulicacid), in accordance with an embodiment of the invention.

FIG. 16 is a TGA plot for 70:30 poly(ferulic acid-co-dihydroferulicacid), in accordance with an embodiment of the invention.

FIG. 17 is a DSC thermogram of 90:10 poly(ferulic acid-co-dihydroferulicacid), in accordance with an embodiment of the invention.

FIG. 18 is a TGA plot for 90:10 poly(ferulic acid-co-dihydroferulicacid), in accordance with an embodiment of the invention

FIG. 19 is a DSC thermogram of poly(ferulic acid), in accordance with anembodiment of the invention.

FIG. 20 is a TGA plot for poly(ferulic acid), in accordance with anembodiment of the invention

DETAILED DISCLOSURE

Embodiments of the invention are directed to a novel biorenewablepolymer, poly(dihydroferulic acid) (PHFA), and a method for itspreparation by the step-growth polycondensation of a biorenewablemonomer, acetyldihydroferulic acid. The preparation of the biorenewablepolymer begins with the aromatic aldehyde, vanillin, which can beextracted from lignin at up to about 5% by mass of the lignin. As shownin FIG. 1, vanillin is condensed with acetic anhydride in the presenceof a base, a Perkin reaction, to yield acetylferulic acid. Aceticanhydride can be prepared commercially from biorenewable sources.Acetylferulic acid is subsequently reduced with H₂ toacetyldihydroferulic acid. Polytransesterification of theacetyldihydroferulic acid results in the desired PHFA with theliberation of acetic acid, which can be recycled for the preparation ofacetic anhydride if desired. As the PHFA results from the selfcondensation of acetyldihydroferulic acid, no molecular weightlimitations due to a stoichiometric imbalance of reactive functionalityis possible. The net transformation from vanillin to PHFA has thepotential for the very efficient use of the renewable resources. Inanother embodiment dihydroferulic acid can be polymerized to PHFA.

The PHFA is biorenewable and is potentially recyclable. PHFA is apolyethylene terephthalate (PET) mimic, displaying a T_(m) of 234° C.and a T_(g) of 73° C. Hence, the thermal processing and recycling ofPHFA and PET, T_(m)=265° C. and T_(g)=67° C., is inherently similar, andfor many applications the thermal properties of PHFA are arguably animprovement over those of PET. Devices, such as plastic water bottles,which are commonly made of PET, have uses confined by the thermalproperties of the amorphous phase reflected in the T_(g), and can beformed from PHFA with no compromise. Since most PET devices are rarelysubjected to extremely high temperatures during routine use, the lowerT_(m) of PHFA implies that it can be readily substituted and allow afacile processability with lower energy consumption. PHFA also has acooling-cycle crystallization temperature that is 17° C. higher (207°C.) than that of PET (190° C.), suggesting a faster rate ofcrystallization which is conducive to greater throughput of PHFA devicesduring extrusion, spinning, or molding processes than is possible forPET that has a lamentably slow crystallization rate. Additionally, PHFAtypically exhibits a peak decomposition temperature near 462° C. (50%mass loss under nitrogen, as measured by thermal gravimetric analysis),which is comparable to that of PET (470° C.).

In one embodiment of the invention, the polymerization method forformation of PHFA involves melting acetyldihydroferulic acid in thepresence of a catalyst. The catalyst can be any that can be used for thepolymerization to PET such as Sb₂O₃. Additionally other oxides,alkoxides or acetates of Sb, Ti, Ge, Hg, Si, Zr, Al, or Zn can be used,for example Zn(OAc)₂.2H₂O. Polycondensation can be carried out attemperatures as low as about 200 to 220° C. but can be carried out athigher temperatures in excess of 220° C. but below about 370° C., forexample 280 to 300° C. The polymerization can be carried out under adynamic vacuum to effectively remove acetic acid and drive thepolymerization. Traditional “solid stating” and either standard or flowinduced “crystallizing” steps that are used for the preparation of PETcan be included for the processing of PHFA.

The method employed to provide the biorenewable acetyldihydroferulicacid can provide other aromatic/aliphatic polyesters from a phenylsubstituted 3-(4-acetoxyphenyl)propanoic acid. For example,syringaldehyde, which can also be isolated from lignin, can be convertedinto 3-(4-acetoxy-3,5-dimethoxyphenyl)acrylic acid, reduced to3-(4-acetoxy-3,5-dimethoxyphenyl)propanoic acid and self-condensed to apoly(3-(4-hydroxy-3,5-dimethoxyphenyl)propanoic acid) in an analogousmanner to that for the preparation of PHFA. Hence, any monomer of thestructure:

where R¹, R², R³, R⁴ are independently H or OR where R is C₁ to C₆ alkylcan be employed to prepare an aromatic/aliphatic polyester of thestructure:

where R¹, R², R³, R⁴ are independently H or OR where R is C₁ to C₆alkyl, according to an embodiment of the invention. Thearomatic/aliphatic polyester can have acetoxy terminal units.

Another embodiment of the invention is directed to copolymers ofacetyldihydroferulic acid and acetylferulic acid, as shown in FIG. 10.The copolymers are equivalent to polystyrene with respect to thermaltransitions where the proportions of the comonomers is appropriate, forexample, a 50:50 mixture of monomers by mole results in a copolymer witha T_(g) similar to atactic polystyrene. The properties of the copolymerare readily adjusted by the comonomer mixture used to prepare thecopolymer. In general, as the proportion of acetylferulic acid derivedunits in the copolymer increases, the glass transition temperatureincreases. Therefore, polymers with little crystallinity can be formedwhere the glass transition temperature can range from about 70° C. toabout 140° C. by selection of the appropriate comonomer feed ratio.

Methods and Materials

Unless otherwise noted, all solvents were sparged with nitrogen, driedover molecular sieves using an MBraun Solvent Purification System,dispensed into oven-dried Straus flasks, and degassed by stirring underreduced pressure for 20 minutes. Toluene for polymerization reactionswas distilled from sodium/benzophenone under a nitrogen atmosphere andstored in an oven-dried Straus flask until used. All other chemicals andsolvents were used as received.

Proton nuclear magnetic resonance (¹H NMR) spectra were recorded using aVarian Mercury 300 MHz spectrometer. Chemical shifts are reported inparts per million (ppm) downfield relative to tetramethylsilane (TMS,0.0 ppm) or residual proton in the specified solvent. Coupling constants(0.1) are reported in Hertz (Hz). Multiplicities are reported using thefollowing abbreviations: s, singlet; d, doublet; t, triplet; q, quartet;quin, quintuplet; m, multiplet; br, broad.

Differential scanning chromatographs were obtained with a DSC Q1000 fromTA instruments. About 5-10 mg of each sample were massed and added to asealed pan that went through a heat/cool/heat cycle at 10° C./min.Reported data are from the second full cycle. The temperature rangedepends on the experiment, but was limited to 300° C. by the instrument.

Thermogravimetric analyses were measured under nitrogen with a TGA Q5000from TA Instruments. About 5-10 mg of each sample was heated at 50°C./min from 25-600° C.

Viscosity measurements were performed at 35° C. in a 1:2 mixture ofphenol:1,1,2,2 tetrachloroethane with a CANNON-Ubbelohde type 150viscometer.

(E)3-(4-acetoxy-3-methoxyphenyl)acrylic acid (acetylferulic acid)

In a round bottomed flask, 30.04 g of vanillin (0.197 mol) and 26.0 g ofsodium acetate (0.317 mol) were dissolved in 200 mL of acetic anhydride(2.12 mol). About 1 mL of pyridine was added to the flask and themixture was heated to reflux. After 24 h, the brown solution was pouredover about 500 g of crushed ice and the solution was stirred until theappearance of a yellow-brown solid. The flask was left overnight in thefreezer and a dark yellow solid was obtained by filtration. The crudesolid was recrystallized from acetic acid/water to give 32.3 g of ayellow beige solid in a 69% yield.

¹H NMR (DMSO) (FIG. 2): δ 12.35 (br s, 1H, COOH), 7.56 (d, J=15.9 Hz,1H, Ar—CH), 7.46 (d, J=1.7 Hz, 1H, Ar—H), 7.24 (dd, J=8.2 Hz, 1.7 Hz,1H, Ar—H), 7.09 (d, J=8.2 Hz, 1H, Ar—H), 6.56 (d, J=15.9 Hz, 1H,CHCOOH), 3.8 (s, 3H, OCH₃), 2.24 (s, 3H, CH₃).

¹³C NMR (DMSO) (FIG. 3): δ 168.4, 167.6, 151.1, 143.4, 140.8, 138.3,123.2, 121.3, 119.5, 111.8, 56.0, 20.4.

(E)3-(4-acetoxy-3-methoxyphenyl)acrylic acid (acetylferulic acid)alternate synthesis

In round bottomed flask, 10 g of(E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoic acid (ferulic acid) wasdissolved in 14.7 mL of acetic anhydride and 15 mL of pyridine at roomtemperature with stirring for three hours. The resulting clear liquidwas poured over 300 mL of an ice/deionized water slurry. After one hour,the ice/water mixture was gravity filtered, washed with deionized water,and dried. The resulting white powder was recrystallized in a 5:1mixture of ethyl acetate and water and dried on a Schlenk line with ayield of 86%.

3-(4-acetoxy-3-methoxyphenyl)propanoic acid (acetyldihydroferulic acid)

A 15.0 g (0.064 mol) portion of acetylferulic acid was dissolved in 230mL of a 15:8 by volume mixture of tetrahydrofuran:methanol. The solutionand 1.5 g of 10% palladium on charcoal was placed in a Parr pressurereactor. The reaction mixture was stirred at room temperature under 60psi of hydrogen for 5 hours. The resulting black suspension was filteredthrough celite to remove the palladium on charcoal. The resulting clearbrown solution was dried over magnesium sulfate and concentrated invacuo. The solid was then dissolved in tetrahydrofuran and precipitatedby addition to hexanes giving 12.8 g of an off-white product in 85%yield.

¹H NMR (DMSO) FIG. 4): δ 12.15 (br s, 1H, COOH), 6.98 (s, 1H, Ar—H),6.93 (d, j=7.9 Hz, 1H, Ar—H), 6.76 (d, J=7.9 Hz, 1H, Ar—H), 3.72 (s, 3H,OCH₃), 2.79 (t, J=8.0 Hz, 2H, Ar—CH₂), 2.53 (t, J=8.0 Hz, 2H, CH₂COOH),2.20 (s, 3H. CH₃).

¹³C NMR (DMSO) (FIG. 5): δ 174.1, 168.9, 150.8, 140.1, 137.8, 122.7,120.3, 113.1, 55.9, 35.5, 30.5, 20.7.

3-(4-acetoxy-3-methoxyphenyl)propanoic acid (acetyldihydroferulic acid)alternate synthesis 1

A 15 g portion of acetyldihydroferulic acid, 150 ml, of tetrahydrofuran,and 80 mL of methanol were placed in a Parr pressure reactor containing1.5 grams of 10% palladium on charcoal. The reaction mixture was stirredat 30° C. under 60 psi of hydrogen for five hours. To remove thepalladium on charcoal, the resulting solution was vacuum filteredthrough celite, dried over magnesium sulfate, and condensed in vacuo.The solid was dissolved in a minimum amount of warm tetrahydrofuran(THF) and precipitated in ice cooled hexanes and the solid portionrecrystallized from a 5:1 mixture of ethyl acetate and water and driedon a Schlenk line in a 62% yield.

3-(4-acetoxy-3-methoxyphenyl)propanoic acid (acetyldihydroferulic acid)alternate synthesis 2

A 10 g portion of ferulic acid, 150 mL of THF, and 80 mL of methanolwere placed in a Parr pressure reactor with 1.5 grams of 10% palladiumon charcoal. The reaction mixture was stirred at 30° C. under 60 psi ofhydrogen for 12 hours. To remove the palladium on charcoal, the solutionwas vacuum filtered through celite, dried over magnesium sulfate, andcondensed in vacuo. The solid was dissolved in a minimum amount of warmTHF and poured into ice chilled hexanes and the solid portionrecrystallized from a 5:1 mixture of ethyl acetate and water and driedon the Schlenk line. The crystals of dihydroferulic acid were acetylatedby reaction with 9.6 g of acetic anhydride in the presence of 7.6 mL ofpyridine. The mixture was stirred at room temperature for three hoursand poured over an ice/water slurry (300 mL), to form a whiteprecipitate that was filtered and dried on a Schlenk line, giving a 78%yield.

Polymers

A series of polymerization of acetyldihydroferulic acid was carried outas summarized in the following tables where Table 1 gives thepolymerization conditions and polymer size and viscosity and Table 2gives the thermal properties of the polymers.

Copolymers

A series of copolymerizations of acetylferulic acid andacetyldihydroferulic acid was carried out with the mole and reactionconditions summarized in Table 3. All copolymerizations occurred bymelting the two monomers under nitrogen for two hours at the temperaturerange between 260-280° C. in the presence of one mole % zinc acetate ascatalyst. Vacuum was then applied for six hours, which resulted in abrown-orange solid. The solid was dissolved in a hot 1:1 mixture oftrifluoroacetic acid/dichloromethane. Ice cooled methanol was added tothe copolymer solution resulting in a yellow precipitate, which wasfiltered to isolate copolymer in 38 to 84% yield, as indicated in Table3. Differential Scanning Calorimetry (DSC) and ThermogravimetricAnalysis (TGA) plots for various copolymers 10:90, 30:70, 70:30 and90:10 are shown in FIGS. 11-18, respectively. Differential ScanningCalorimetry (DSC) and Thermogravimetric Analysis (TGA) plots forpoly(ferulic acid) are shown in FIGS. 19 and 20, respectively.

Polymer Molecular Weight Analysis

Viscosity Analysis

Intrinsic viscosity measurements were performed with a Ubbelohdeviscometer. 15 mL of clean 1:2 mixture of phenol:1,1,2,2-tetrachloroethane were poured in the viscometer and allow tothermally equilibrate for 2 h. Exactly 1 mL of about 8 g/L solution ofpolymer was added for each measurement until the final volume is 20 mLin the viscometer giving a final concentration of about 2 g/L.

$\lbrack\eta\rbrack = {{\lim\frac{\eta_{sp}}{c}\mspace{14mu}{with}\mspace{14mu}\eta_{sp}} = \frac{t - {to}}{to}}$c → 0 $\frac{\eta_{sp}}{c} = {f(c)}$From a Kramer plot and extrapolating to infinitely dilute solution(c→0), the intrinsic viscosity is obtained. The value is then related tothe Mark-Houwink constant for PET in the same solvent and temperature.[η]=1.09×10⁻² M _(v) ^(0.84)End Group Analysis

End group analysis was used to determine the degree of polymerization ofthe polymer. In an NMR analysis, the chemical environment for the endgroup is different from that of the repeat unit in the middle of thepolymer chain. For PHFA, as shown in FIG. 6, the end groups arecarboxylic acid and acetyl groups, which bear a methyl group that has achemical shift of about 2.4 ppm. Four aliphatic hydrogens, associatedwith each repeat unit of the chain, resonate near 2.9 to 3.1 ppm. Bymeasuring the integration of the methyl group hydrogens I_(end) by ¹HNMR and that of the methylene hydrogens (I_(n)) present in each repeatunit, the number of repeat units (the degree of polymerization, DP) andby the repeating unit's molecular weight, RU, the number averagemolecular weight of the polymer chain is determined using the followingequation.

${DP} = {{\frac{3}{4} \times \frac{I_{n}}{I_{end}}\mspace{14mu}{and}\mspace{14mu} M_{n}} = {{RU} \times {DP}}}$

TABLE 1 Polymerization results and characterization ofpoly(dihydroferulic acid), PHFA. melt vacuum stirring yield Entry T_(p)(° C.) catalyst^(a) time (h) time (h) (h) (%) [η]^(b) M_(v) ^(c) DP^(d)M_(n) ^(d) acetyl dihydroferulic acid → PHFA 1 2 0200-220  None 2 2 1.583 31 12,900 27 4,800 2 2 200-220 Sb₂O₃ 2 2 0.5 67 29 12,000 23 4,100 32 200-220 Zn(OAc)₂ 2 2 0.5 82 27 11,000 38 6,800 4  2200-220 Zn(OAc)₂ 26 0.5 91 36 15,500 50 8,900 5 2 220-250 Zn(OAc)₂ 2 6 0.5 68 35 14,800100 17,800  6   200-220 Zn(OAc)₂ 2 0.17 — 75 17 6,300 17 3,000 7 220Zn(OAc)₂ 2 6 — 84 — — — — dihydroferulic acid → PHFA 8 2 200-220 Sb₂O₃ 56 — ~5 n.d. n.d. 3.5^(e)   630^(c) ^(a)Catalyst loading = 1 mol %.^(b)Intrinsic viscosity measured with an Ubbelohde viscometer in a 1:2solution of phenol/1,1,2,2-tetrachloroethane at 35° C. ^(c)Intrinsicviscosity (mL/g) calculated with [η] = 1.09 × 10⁻² M_(v) ^(0.84).^(d)Degree of Polymerization measured by ¹H NMR end group analysis.^(e)GPC analysis.

TABLE 2 Differential Scanning Calorimetry (DSC), as shown in FIG. 8, andThermogravimetric Analysis (TGA), as shown in FIG. 9, data for PHFA fromTable 1, entries 1-7.^(a) major minor T_(m) ΔH melt ΔH cryst T 50% EntryT_(g) (° C.) T_(m (° C.)) (° C.) (J/g) T_(c) (° C.)^(a) (J/g)^(a)decomp. (° C.)^(b) 1 74.0 242.6 228.9 47.7 207.1 51.0 471 2 73.4 234.4216.9 43.5 193.4 48.1 462 3 73.3 234.1 220.4 39.8 195.8 44.9 461 4 66.9231.2 215.2 43.2 189.3 46.9 464 5 66.6 216.3 — 27.9 162.2 26.8 456 665.1 240.3 219.6 51.4 203.2 54.6 452 7 73.0 242.9 228.9 38.6 204.5 42.2422 ^(a)Crystallization was observed on the cooling scan, but not theheating scan. ^(b)The temperature at which 50% mass loss is observed.TGA was performed under nitrogen.

TABLE 3 Polymerization results and characterization of copolymerizationof (A) acetyferulic and (B) acetyldihydroferulic acid (PHFA). T 50%Entry % A % B Stirring^(a) Yield % T_(g) (° C.) T_(m) (° C.) (° C.) 1 0100 0.5 84 73 243 422 2 10 90 1.5 47 73 217 422 3 20 80 2 46 70 213 4194 30 70 1.5 35 86 NA 422 5 40 60 1.5 78 87 NA 404 6 50 50 1.5 82 95 NA417 7 60 40 2 71 115 NA 440 8 70 30 1.5 68 123 NA 435 9 80 20 1.5 79 125218 438 10 90 10 1.5 47 140 227 435 11 100 0 2 38 158 NA 446 12 100 0 256 155 290 467 ^(a)Time in hours that stirring stopped as the viscosityof the mixture increased.

Poly(3-(4-hydroxy-3-methoxyphenyl)propanoic acid) (poly(dihydroferulicacid), PHFA)

Table 1, Entry 1.

1.61 g (6.8 mmol) of acetyldihydroferulic acid were melted undernitrogen for 2 h and vacuum was applied for 2 h leaving a brown solidthat was dissolved in a mixture of trifluoroacetic acid/dichloromethaneand precipitated with methanol. 1.0 g of off-white product was obtainedby filtration in 83% yield.

¹H NMR (CF₃COOD/CDCl₃): δ 6.92 (m, 3H, Ar—H), 3.84 (s, 3H, OCH₃), 3.11(m, 2H, CH₂), 3.00 (m, 2H, CH₂).

¹³C NMR (DMSO): δ 176.1, 150.9, 140.6, 138.3, 123.2, 121.8, 113.9, 56.6,36.2, 31.2.

Table 1, Entry 2.

1.61 g (6.8 mmol) of acetyldihydroferulic acid and 0.021 g (0.072 mmol)of antimony trioxide (1 mol %) were melted under nitrogen for 2 h andvacuum was applied for 2 h leaving a brown solid that was dissolved in amixture of trifluoroacetic acid/dichloromethane and precipitated withmethanol. 0.8 g of off-white product was obtained by filtration in 67%yield.

¹H NMR (CF₃COOD/CDCl₃): δ 6.88 (m, 3H, Ar—H), 3.80 (s, 3H, OCH₃), 3.07(m, 2H, CH₂), 2.96 (m, 2H, CH₂).

¹³C NMR (CF₃COOD/CDCl₃): δ 175.5, 150.4, 140.1, 137.8, 122.6, 120.0,113.4, 56.1, 35.8, 30.7.

Table 1, Entry 3.

1.63 g (6.8 mmol) of acetyldihydroferulic acid and 0.018 g (0.082 mmol)of zinc diacetate dihydrate (1 mol %) were melted under nitrogen for 2 hand vacuum was applied for 2 h leaving a brown solid that was dissolvedin a mixture of trifluoroacetic acid/dichloromethane and precipitatedwith methanol. 1.0 g of off-white product was obtained by filtration in82% yield.

¹H NMR (CF₃COOD/CDCl₃): 6.92 (m, 3H, Ar—H), 3.84 (s, 3H, OCH₃), 3.11 (m,2H, CH₂), 3.00 (m, 2H, CH₂).

¹³C NMR (CF₃COOD/CDCl₃): 175.4, 150.4, 140.0, 137.8, 122.6, 121.7,113.3, 56.0, 35.7, 30.7.

Table 1, Entry 4.

1.63 g (6.8 mmol) of acetyldihydroferulic acid and 0.018 g (0.082 mmol)of zinc diacetate dihydrate (1 mol %) were melted under nitrogen for 2 hand vacuum was applied for 6 h leaving a brown solid that was dissolvedin a mixture of trifluoroacetic acid/dichloromethane and precipitatedwith methanol. 1.1 g of off-white product was obtained by filtration in91% yield.

¹H NMR (CF₃COOD/CDCl₃) (FIG. 6): δ 6.90 (m, 3H, Ar—H), 3.83 (s, 3H,OCH₃), 3.10 (m, 2H, CH₂), 2.99 (m, 2H, CH₂).

¹³C NMR (CF₃COOD/CDCl₃) (FIG. 7): δ 175.5, 150.4, 140.0, 137.7, 122.6,121.1, 113.3, 56.0, 35.7, 30.7.

Table 1, Entry 5.

1.61 g (6.8 mmol) of acetyldihydroferulic acid and 0.017 g (0.077 mmol)of zinc diacetate dihydrate (1 mol %) were melted under nitrogen at220-250° C. for 2 h and vacuum was applied for 6 h leaving a brown solidthat was dissolved in a mixture of trifluoroacetic acid/dichloromethaneand precipitated with methanol. 0.82 g of off-white product was obtainedby filtration in 68% yield.

¹H NMR (CF₃COOD/CDCl₃): δ 6.88 (m, 3H, Ar—H), 3.80 (s, 3H, OCH₃), 3.07(m, 2H, CH₂), 2.96 (m, 2H, CH₂).

¹³C NMR (CF₃COOD/CDCl₃): δ 175.0, 150.4, 139.8, 137.7, 122.5, 121.0,113.1, 56.0, 35.7, 30.7.

Table 1, Entry 6.

1.61 g (6.8 mmol) of acetyldihydroferulic acid and 0.017 g (0.077 mmol)of zinc diacetate dihydrate (1 mol %) were melted under nitrogen for 2 hand vacuum was applied for 10 min, leaving a brown solid that wasdissolved in a mixture of trifluoroacetic acid/dichloromethane andprecipitated with methanol. 0.90 g of off-white product was obtained byfiltration in 75% yield.

¹H NMR (CF₃COOD/CDCl₃): δ 6.88 (m, 3H, Ar—H), 3.80 (s, 3H, OCH₃), 3.07(m, 2H, CH₂), 2.96 (m, 2H, CH₂).

¹³C NMR (CF₃COOD/CDCl₃): δ 176.0, 150.5, 140.4, 138.0, 122.8, 121.6,113.7, 56.2, 35.9, 30.9.

Table 1, Entry 7.

1.63 g (6.8 mmol) of acetyldihydroferulic acid and 0.018 g (0.082 mmol)of zinc diacetate dihydrate (1 mol %) were melted under nitrogen for 2 hand vacuum was applied for 6 h leaving a brown solid that was dissolvedin a mixture of trifluoroacetic acid/dichloromethane and precipitatedwith methanol. 1.02 g of off-white product was obtained by filtration in84% yield.

3-(4-hydroxy-3-methoxyphenyl)propanoic acid (dihydroferulic acid)

A solution was prepared from 8.0 g (0.034 mol) of acetyldihydroferulicacid and 4.7 g (0.118 mol) of sodium hydroxide in 100 mL of water andrefluxed for 5 h. After cooling to room temperature, the aqueoussolution was acidified with hydrochloric acid and extracted withdichloromethane. The organic layer was washed with brine and dried overmagnesium sulfate. The evaporation of the solvent left a yellow crudeproduct that was dissolved in dichloromethane and precipitated inhexanes to yield 5.5 g of an off-white powder in 83% yield.

¹H NMR (CDCl₃): δ 6.87 (d, J=8.0 Hz, 1H, Ar—H), 6.73 (br s, 1H, Ar—H),6.71 (d, J=8.0 Hz, 1H, Ar—H), 3.88 (s, 3H, OCH₃), 2.90 (t, 0.1=7.8 Hz,2H, Ar—CH₂), 2.70 (t, J=7.8 Hz, 2H, CH₂COOH).

¹³C NMR (CDCl₃): δ 179.2, 146.4, 144.1, 132.0, 120.8, 114.4, 110.9,55.8, 36.0, 30.3.

Oligo(3-(4-hydroxy-3-methoxyphenyl)propanoic acid) (oligo(dihydroferulicacid))

Table 1, Entry 8.

1.61 g (8.2 mmol) of dihydroferulic acid and 0.0195 g (0.067 mmol) ofantimony trioxide (1 mol %) were heated under nitrogen for 5 h andvacuum was applied for 6 h. At the end of the 6 h period, the productwas still a brown melt in the flask. The product was dissolved indichloromethane/trifluoroacetic acid and only 0.07 g (5%) of productprecipitated upon addition of methanol. The methanol was subjected torotary distillation, leaving 1.5 g of brown, amorphous solid that wasanalyzed by GPC showing only low molecular weight material.

All patents, patent applications, provisional applications, andpublications referred to or cited herein are incorporated by referencein their entirety, including all figures and tables, to the extent theyare not inconsistent with the explicit teachings of this specification.

It should be understood that the examples and embodiments describedherein are for illustrative purposes only and that various modificationsor changes in light thereof will be suggested to persons skilled in theart and are to be included within the spirit and purview of thisapplication.

We claim:
 1. A biorenewable thermoplastic poly(dihydroferulic acid),consisting of repeating units of the structure

and end-groups.
 2. The biorenewable thermoplastic poly(dihydroferulicacid) of claim 1, wherein the poly(dihydroferulic acid) has at least oneacetoxy end-group.
 3. A method of preparing poly(dihydroferulic acid)according to claim 1 comprising: providing acetyldihydroferulic acid anda catalyst; and polymerizing the acetyldihydroferulic acid to apoly(dihydroferulic acid) with the liberation of acetic acid.
 4. Themethod of claim 3, wherein the acetyldihydroferulic acid is derived fromone or more biorenewable sources.
 5. The method of claim 4, wherein thebiorenewable source is lignin or rice bran.
 6. The method of claim 3,wherein the catalyst comprises an oxide, alkoxide or acetate of Sb, Ti,Ge, Hg, Si, Zr, Al, or Zn.
 7. The method of claim 6, wherein thecatalyst is Zn(OAc)₂.
 8. The method of claim 3, wherein polymerizing iscarried out under vacuum.
 9. The method of claim 3, wherein polymerizingis carried out at a temperature of 200 to 300° C.